4-hydroxybenzyl alcohol 4-o-bata-d-glucoside
Gastrodin
CAS: 62499-27-8
Molecular Formula: C13H18O7
4-hydroxybenzyl alcohol 4-o-bata-d-glucoside - Names and Identifiers
| Name | Gastrodin |
| Synonyms | Gastrodin Gastro enterical 4-(β-D-Glucopyranosyloxy)benzyl alcohol 4-O-BETA-D-GLUCOPYRANOSYLOXYBENZYL ALCOHOL p-(Hydroxymethyl)phenyl β-D-glucopyranoside 4-(Hydroxymethyl)phenyl β-D-glucopyranoside 4-hydroxybenzyl alcohol 4-o-bata-d-glucoside 4-Hydroxybenzyl alcohol 4-O-bata-D-glucoside 4-(hydroxymethyl)phenyl beta-D-glucopyranoside (2R,3S,4S,5R,6S)-2-HYDROXYMETHYL-6-(4-HYDROXYMETHYL-PHENOXY)-TETRAHYDRO-PYRAN-3,4,5-TRIOL |
| CAS | 62499-27-8 |
| EINECS | 683-202-7 |
| InChI | InChI=1/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1 |
4-hydroxybenzyl alcohol 4-o-bata-d-glucoside - Physico-chemical Properties
| Molecular Formula | C13H18O7 |
| Molar Mass | 286.28 |
| Density | 1.504±0.06 g/cm3(Predicted) |
| Melting Point | 169-170° |
| Boling Point | 563.2±50.0 °C(Predicted) |
| Specific Rotation(α) | D20 -17.5° (c = 1 in pyridine) |
| Flash Point | 294.4°C |
| Solubility | Soluble in water, methanol, ethanol, insoluble in chloroform and ether |
| Vapor Presure | 1.6E-13mmHg at 25°C |
| Appearance | White needle crystal |
| Color | White to Off-White |
| Maximum wavelength(λmax) | ['272nm(MeOH)(lit.)'] |
| Merck | 14,4375 |
| pKa | 9.10(at 25℃) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.638 |
| MDL | MFCD00272169 |
| Physical and Chemical Properties | Soluble in water, methanol, ethanol, insoluble in chloroform and ether. Extraction of dried root blocks derived from Gastrodia elata, a Orchidaceae plant |
4-hydroxybenzyl alcohol 4-o-bata-d-glucoside - Risk and Safety
| RTECS | LZ5776885 |
| HS Code | 29329990 |
4-hydroxybenzyl alcohol 4-o-bata-d-glucoside - Reference
| Reference Show more | 1. Li Feng, Jin Hong, Huang Yechuan. Preparation of microencapsulation of Gastrodia elata extract [J]. Science and Technology of Food Industry, 2012(20):195-198. 2. Wei Yalei, Cai Wei, Zhang Zhichao, et al. Study on the components of Gastrodia elata extract into blood after intragastric administration to rats [J]. China pharmaceuticals, 2015, 24(021):8-10. 3. Yu Qian, Zhang Yi, Su Yao, etc. A preliminary study on the preparation of liquid fermented wine from Gastrodia elata Blume and its residue [J]. Food Science and Technology, 2020, v.45;No.341(03):110-114. 4. Ginger, Yang Songwei, Zhu Tianbi, et al. Pharmacological effects and mechanism of gastrodin on amyotrophic lateral sclerosis cell model [J]. New Traditional Chinese Medicine and Clinical Pharmacology, 2017(06):729-733. 5. Xiulin Li, Menghua Tian. Comparison of extraction methods for main active components of Gastrodia elata in Zhaotong [J]. Yunnan chemical industry, 2017(8). 6. Fan Hui, Tian Yuan. Optimization of ethanol extraction process of Tianma Anshen granules by orthogonal test [J]. Chinese Journal of Experimental prescriptions, 2015, 21(7):21-23. 7. Zheng Haifei, Li Bin, Wu Xintong, et al. Study on the molecular mechanism of the treatment of migraine by adenosine pathway [J]. Journal of Stroke and neurological diseases, 2020, 037(003):255-260. 8. Chen Songwang, Wu Ting, Li Huang, et al. Study on quality standard of changmaile capsules [J]. Fujian Medical Journal, 2020, 042(001):127-132. 9. Li Ping, Hao Min, Su Lin, et al. Study on quality of Gastrodia elata Blume by UPLC fingerprint combined with multi-component content determination [J]. Chinese herbal medicine 2018 49(23):186-192. 10. Zhu Hongyan, Jiang ran, he Zhongmei, etc. Content analysis of gastrodin, gastrodin and polysaccharide in different processed products of Gastrodia elata [J]. Chinese Pharmaceutical Journal 2017 052(023):2062-2065. 11. Tian Meng Hua Yuan Tianjun Zhou Rui Yang Xin Zhou. Analysis on the difference of effective components in different habitats and variant Gastrodia elata [J]. Chinese patent medicine 2020 42(07):1824-1829. 12. Yu Xiaojing, Zhang lunar November, Li Siyu, et al. Establishment of HPLC fingerprint of water extract of Gastrodia elata and its identification [J]. Chinese traditional medicines, 2018, 40(12):2698-2702. 13. Li Ping, Xu Jinguo, JID, et al. Study on the correlation between traditional traits and internal quality of Gastrodia elata [J]. Chinese Journal of Traditional Chinese Medicine, 2019, v.44(20):158-164. 14. Wang Liping, Zhang Huailiang. Simultaneous determination of six components in Tianma Xifeng granules by HPLC [J]. Journal of Medicine Forum 2018 v.39(06):20-23. 15. Pei Wenqiang, single Yi, Zhang Yougang, Jia Xianhui, Wang Haiyang, Wang Xiaojing, Tian Qingping, Han Liwen, Yao Qingqiang. Study on antiepileptic effect and potential mechanism of Gastrodia elata based on zebrafish model and integrated pharmacology platform of traditional Chinese medicine [J]. Chinese herbal medicine, 2021,52(07):2003-2010. 16. Song Wei, Chen Jinbo, Zhang Defu, ZHENG Hai Fei, Song Xiao-Wen, Dong Xiao-Meng, Lu Wen-Xian. Therapeutic effect and mechanism of gastrodin intraperitoneal injection on chronic migraine rats [J]. Shandong medicine, 2021,61(04):10-14. 17. Gong Mengqi, Sun Qian, Li Zhen. Optimization of extraction process of gastrodin from Gastrodia elata and its inhibitory activity on α-glucosidase [J]. China fruit vegetables, 2020,40(09):14-17 23. 18. Weng liancin, Kuang Shixiang, Xue Hong, He qiansong, Wang Qiang, Liu Jianhui, Zhao Zhilan, Li Yan. Therapeutic effect of gastrodin on pentylenetetrazol-induced epileptic model rats and its mechanism of autophagy and apoptosis [J]. Journal of difficult diseases, 2021,20(01):77-82. 19. Liu, Mengyujie, et al. "Discovery and identification of proangiogenic chemical markers from Gastrodiae rhezoma-based on zebra fish model and metabonomics approach." Phytochemical Analysis 31.6 (2020): 835-845.https:// doi.org/10.1002/pci.2949 20. [IF = 5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 21. [IF=4.759] Wenhua Ji et al."Water-compatible micron-sized monodisperse molecularly imprinted beads for selective extraction of five iridoid glycosides from Cornus officinalis fructus."J Chromatogr A. 2017 Jun;1504:1 22. [IF=9.783] Huiping Bi et al."Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction."Metab Eng. 2022 Jan;69:15 23. [IF=5.396] Jianzheng He et al."Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease."Food Funct. 2021 Aug;12(17):7816-7824 24. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 25. [IF=2.772] Mengyujie Liu et al."Discovery and identification of proangiogenic chemical markers from Gastrodiae Rhizoma based on zebrafish model and metabolomics approach."Phytochem Analysis. 2020 Nov;31(6):835-845 26. [IF=6.475] Zhen Wu et al."How steaming and drying processes affect the active compounds and antioxidant types of Gastrodia elata Bl. f. glauca S. chow."FOOD RESEARCH INTERNATIONAL. 2022 Jul;157:111277 |
4-hydroxybenzyl alcohol 4-o-bata-d-glucoside - Introduction
Pharmacological effects: It has good sedative and sleeping effects, and relieves neurasthenia, insomnia, and headache symptoms. Gastrodia elata can treat pain, dizziness, numbness of limbs, convulsion and convulsion. Clinical treatment of vertebrobasilar artery insufficiency; treatment of vestibular neuronitis; treatment of vertigo.
Last Update：2022-10-16 17:27:21
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Spot supply
Product Name: Gastrodin Visit Supplier Webpage Request for quotationCAS: 62499-27-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: Gastrodin Visit Supplier Webpage Request for quotationCAS: 62499-27-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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